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PLLACUBE® is available exclusively to registered clinic accounts — Apply for access

Load video: PLLACUBE illustration video Derma Essence Canada

ALL-IN-ONE
Skinbooster
Powered by InCUBE™ Technology

Developed and manufactured by LabInCube Korea through advanced biomolecular research, PLLACUBE delivers multi-active rejuvenation in one stabilized complex — engineered for radiant, resilient skin.

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PLLACUBE unites six clinically proven bioactive ingredients in one stabilized system:

PLLA PDRN EXO Vitamin C Glutathione Hyaluronic Acid

Clinic-ready highlights

Best for dull, dehydrated, post-laser, and texture-focused patients

Pairs with microneedling and RF microneedling

No refrigeration required before reconstitution

Fast 2-minute reconstitution

Topical-use protocol for North American clinics

Clinic onboarding and protocol support included

The Science Behind PLLACUBE

Nobel-Level Science.
Clinic-Ready Innovation.

PLLACUBE is developed by LabInCube, a Korean biotech founded on research from one of the world's most recognized molecular science laboratories — with peer-reviewed publications in leading international journals.

2025 Nobel Prize Chemistry

Built on MOF science awarded the Nobel Prize in Chemistry. LabInCube's founder trained directly under Prof. Omar Yaghi at UC Berkeley.

Seoul National University Hospital

Co-authored peer-reviewed skin research with SNUH — Korea's most prestigious academic medical center, validating MOF technology in skin applications.

Clinically Evaluated

3-week GCP-certified clinical study at Human Co., Ltd. Skin Clinical Trial Center, Korea. Significant results across 5 skin parameters.

5 Registered Patents

Protected by 5 Korean Intellectual Property Office patents including Patent No. 10-2488551 for INCUBE™ encapsulation technology.


Advanced Healthcare Materials · Wiley · 2023

Zirconium-Based Metal-Organic Framework Capable of Binding Proinflammatory Mediators Promotes Wound Healing Through a Multiscale Adsorption Mechanism

Institutions: Sookmyung Women's University · Seoul National University Bundang Hospital · LabInCube Co., Ltd.
DOI: 10.1002/adhm.202301679

In Vivo · 2024

Effect of Silicone Patch Containing Metal-Organic Framework on Hypertrophic Scar Suppression

Institutions: Seoul National University Hospital · Seoul National University College of Medicine · LabInCube Co., Ltd.
DOI: 10.21873/invivo.13430


Used in leading Korean clinics

Leaders Dermatology Clinic Obliv Clinic Clinic AL Acmedi Korea
	PLLACUBE skinbooster in clinic setting – Korea-developed skincare by LabinCube
 Advanced Skincare Science

Patented INCUBE™ Technology  

 INCUBE™ Technology  (Patent No. 10-2488551) is designed to stabilize, protect, and optimize the controlled release of key cosmetic ingredients, optimizing ingredient performance for skincare benefits.

PLLACUBE PiNk VOL PLLA + PN skinbooster vials displayed with lab glassware, demonstrating professional-use formulation for skin hydration, elasticity, and radiance
Dermatologist-Tested for Professional Use

All-IN-ONE Cosmetic Skinbooster

Clinically evaluated in a cosmetic study at the Human Co., Ltd. Skin Clinical Trial Center (Republic of Korea), demonstrating improvements in skin hydration, elasticity, and brightness over three weeks under dermatological supervision.

PLLACUBE vial displayed on multi-porous INCUBE™ material spheres, representing fast-dissolving cosmetic formulation technology for professional use
Supports Ingredient Integrity for Reliable Formulations

INCUBE™ Multi-Porous Material

Powered by LTQ Technology and INCUBE™ Multi-Porous Material, PLLACUBE dissolves quickly and evenly, ensuring a smooth and well-balanced formulation. Designed for professional use, this process supports consistent preparation and effortless application.

COSMETIC SKINBOOSTER

PLLACUBE

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PiNk Vol. skinbooster vial containing 100mg (30mg PLLA), developed in Korea with Patent InCube Technology
PLLACUBE Original skinbooster vial containing 100mg (20mg PLLA), developed in Korea with Patent InCube Technology
PiNk Vol. skinbooster vial containing 100mg (30mg PLLA), developed in Korea with Patent InCube Technology

Official PLLACUBE Canada & U.S Distributor

Discover Derma Essence Canada — the official distributor of PLLACUBE, a next-generation cosmetic skinbooster developed by LabinCube Korea. Powered by patented InCube™ Technology, PLLACUBE is designed for professional use and formulated to support visible improvements in skin elasticity, hydration, and radiance. Each vial unites clinically evaluated ingredients including PLLA (Poly-L-Lactic Acid), PDRN, Vitamin C, Glutathione, plant-derived exosomes, and Hyaluronic Acid—all stabilized for optimal skin performance.

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