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PLLACUBE Original professional cosmetic skinbooster
PLLA Vitamin C PDRN EXO Glutathione HA
PLLA Vitamin C PDRN EXO Glutathione HA

KOREA-DEVELOPED · PROFESSIONAL SKINBOOSTER

Fresh with InCube™ Technology.

Advanced Korean skin science powered by patented InCube™ Technology, developed for modern professional skincare.

Advanced Korean skin science powered by patented InCube™ Technology.

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Made in Korea Professional Use Canada & U.S.

THE SCIENCE INSIDE PLLACUBE

Six Actives.
One Advanced Formula.

Developed by LabInCube Korea, PLLACUBE Original combines PLLA with PDRN, Houttuynia Cordata Extract, Vitamin C, Glutathione and Hyaluronic Acid — powered by InCube™ materials technology for modern professional skincare.

30–80 μm Uniform PLLA particle range
< 1 min Instant hydration technology
6 Actives One professional formula
Explore the Science
POWERED BY InCube™ Storage Platform
Technology
01
PLLA Poly-L-Lactic Acid
02
PDRN Sodium DNA
03
Houttuynia Cordata Extract
04
Hyaluronic Acid Sodium Hyaluronate
05
Glutathione Antioxidant active
06
Vitamin C Ethyl Ascorbyl Ether
PLLA PDRN Houttuynia HA Vitamin C Glutathione

ENGINEERED PLLA

Precision in
Every Particle.

PLLACUBE is engineered with controlled PLLA microspheres designed for uniformity in both particle size and morphology.

30–80 μm Controlled particle range
Near-Spherical Uniform morphology

SEM imaging highlights the distinct morphology of LabInCube engineered PLLA microspheres compared with a reference PLLA sample.

Discover PLLACUBE Technology
LABINCUBE PLLA 01
SEM image of LabInCube PLLA microspheres with uniform spherical morphology and 30 to 80 micrometer particle range
30–80 μm
Uniform Microspheres Controlled size · Near-spherical morphology
ENGINEERED
REFERENCE PLLA 02
SEM reference image showing PLLA particles with irregular morphology
Reference Morphology Irregular particle shape · Variable morphology
REFERENCE

Engineered for a more controlled and consistent particle profile.

BUILT FOR PROFESSIONAL PRACTICE

Designed for the clinic.
Simple from start to finish.

PLLACUBE is designed to fit naturally into modern aesthetic practice — from preparation and storage to professional protocol guidance and partner support.

Professional clinic preparing PLLACUBE Original
CLINIC-READY WORKFLOW
01

Simple Preparation

Streamlined preparation designed for an efficient professional workflow.

02

Professional Protocols

Developed for professional skincare protocols in modern aesthetic practices.

03

Convenient Storage

Designed for convenient clinic inventory and preparation before reconstitution.

04

Clinic Partner Support

Professional onboarding, protocol guidance and support for PLLACUBE partner clinics.

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Made in Korea Professional Use
Professional clinic preparing PLLACUBE Original
CLINIC-READY WORKFLOW
PROFESSIONAL PRACTICE Designed around
the clinic workflow.

THE SCIENCE BEHIND PLLACUBE

From MOF Science
to Aesthetic Innovation.

PLLACUBE is developed by LabInCube Korea — translating advanced porous-material research into patented technology for professional cosmetic formulations.

01

MOF MATERIAL SCIENCE

2025 Nobel Prize
in Chemistry

The 2025 Nobel Prize in Chemistry recognized the development of metal–organic frameworks — the advanced porous-material field behind LabInCube's research foundation.

02

RESEARCH LINEAGE

From the Yaghi
Research Environment

LabInCube founder Prof. Kyung Min Choi previously conducted postdoctoral research in Prof. Omar M. Yaghi's laboratory at UC Berkeley.

03

PEER-REVIEWED RESEARCH

Academic Research
Collaboration

Published MOF studies include researchers affiliated with LabInCube, Seoul National University Bundang Hospital, Seoul National University and Sookmyung Women's University.

04

PROTECTED TECHNOLOGY

Patented
InCube™ Platform

InCube™ is supported by Korean Patent No. 10-2488551, covering a cyclodextrin-based metal–organic framework designed for controlled active-material delivery.

CLINICALLY EVALUATED FORMULATION

Science translated into measurable skin outcomes.

3 Weeks Cosmetic evaluation
Korea Human Skin Clinical Testing
PLLACUBE Finished-formula evaluation

SELECTED RESEARCH

Peer-reviewed publications

MOF · Biomaterials · Skin Research
01

ADVANCED HEALTHCARE MATERIALS · 2024

Zirconium-Based Metal-Organic Framework Capable of Binding Proinflammatory Mediators in Hydrogel Form Promotes Wound Healing Through a Multiscale Adsorption Mechanism

Sookmyung Women's University · Seoul National University Bundang Hospital · LabInCube Co., Ltd.

DOI 10.1002/adhm.202301679
02

IN VIVO · 2024

Effect of Silicone Patch Containing Metal-Organic Framework on Hypertrophic Scar Suppression

Seoul National University Bundang Hospital · Seoul National University College of Medicine · LabInCube Co., Ltd.

DOI 10.21873/invivo.13430

RESEARCH AFFILIATIONS REPRESENTED IN PUBLISHED WORK

Sookmyung Women's University SNU Bundang Hospital Seoul National University LabInCube R&D
Packaging of PLLACUBE PiNk VOL and PLLACUBE Original skinbooster boxes with INCUBE™ technology, designed for professional-use skincare
1

COSMETIC SKINBOOSTER

PLLACUBE

1
PLLACUBE Original cosmetic skinbooster vial product photo – Canada distributor
Pllacube Original
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PiNk Vol. skinbooster vial containing 100mg (30mg PLLA), developed in Korea with Patent InCube Technology
PLLACUBE Original skinbooster vial containing 100mg (20mg PLLA), developed in Korea with Patent InCube Technology
PiNk Vol. skinbooster vial containing 100mg (30mg PLLA), developed in Korea with Patent InCube Technology

Official PLLACUBE Canada & U.S Distributor

Discover Derma Essence Canada — the official distributor of PLLACUBE, a next-generation cosmetic skinbooster developed by LabinCube Korea. Powered by patented InCube™ Technology, PLLACUBE is designed for professional use and formulated to support visible improvements in skin elasticity, hydration, and radiance. Each vial unites clinically evaluated ingredients including PLLA (Poly-L-Lactic Acid), PDRN, Vitamin C, Glutathione, plant-derived exosomes, and Hyaluronic Acid—all stabilized for optimal skin performance.

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