ALL-IN-ONE
Skinbooster
Powered by InCUBE™ Technology
Developed and manufactured by LabInCube Korea through advanced biomolecular research, PLLACUBE delivers multi-active rejuvenation in one stabilized complex — engineered for radiant, resilient skin.
Learn MorePLLACUBE unites six clinically proven bioactive ingredients in one stabilized system:




Clinic-ready highlights
Best for dull, dehydrated, post-laser, and texture-focused patients
Pairs with microneedling and RF microneedling
No refrigeration required before reconstitution
Fast 2-minute reconstitution
Topical-use protocol for North American clinics
Clinic onboarding and protocol support included




The Science Behind PLLACUBE
Nobel-Level Science.
Clinic-Ready Innovation.
PLLACUBE is developed by LabInCube, a Korean biotech founded on research from one of the world's most recognized molecular science laboratories — with peer-reviewed publications in leading international journals.
2025 Nobel Prize Chemistry
Built on MOF science awarded the Nobel Prize in Chemistry. LabInCube's founder trained directly under Prof. Omar Yaghi at UC Berkeley.
Seoul National University Hospital
Co-authored peer-reviewed skin research with SNUH — Korea's most prestigious academic medical center, validating MOF technology in skin applications.
Clinically Evaluated
3-week GCP-certified clinical study at Human Co., Ltd. Skin Clinical Trial Center, Korea. Significant results across 5 skin parameters.
5 Registered Patents
Protected by 5 Korean Intellectual Property Office patents including Patent No. 10-2488551 for INCUBE™ encapsulation technology.
Advanced Healthcare Materials · Wiley · 2023
Zirconium-Based Metal-Organic Framework Capable of Binding Proinflammatory Mediators Promotes Wound Healing Through a Multiscale Adsorption Mechanism
In Vivo · 2024
Effect of Silicone Patch Containing Metal-Organic Framework on Hypertrophic Scar Suppression
Used in leading Korean clinics
Leaders Dermatology Clinic Obliv Clinic Clinic AL Acmedi Korea
Official PLLACUBE Canada & U.S Distributor
Discover Derma Essence Canada — the official distributor of PLLACUBE, a next-generation cosmetic skinbooster developed by LabinCube Korea. Powered by patented InCube™ Technology, PLLACUBE is designed for professional use and formulated to support visible improvements in skin elasticity, hydration, and radiance. Each vial unites clinically evaluated ingredients including PLLA (Poly-L-Lactic Acid), PDRN, Vitamin C, Glutathione, plant-derived exosomes, and Hyaluronic Acid—all stabilized for optimal skin performance.




